A Simple, Transition Metal Catalyst‐Free Method for the Design of Complex Organic Building Blocks Used to Construct Porous Metal–Organic Frameworks

The design of metal–organic frameworks (MOFs) having large pore sizes and volumes often requires the use complex organic ligands, currently synthesized using costly time-consuming palladium-catalyzed coupling chemistry. Thus, in present work, a new strategy for ligand is reported, where piperazine dihydrophenazine units are used as substitutes benzene rings, which basic building block most MOF ligands. This chemistry, based on simple, nucleophilic aromatic substitution (SNAr) reactions, transition metal catalyst-free construction 21 new, carboxylate-based ligands with varying sizes, shapes, denticity 15 linear di- tetra-nitriles. Moreover, to demonstrate utility blocks, 16 structurally diverse MOFs surface areas up 3100 m2 g−1 were also synthesized.